National Conference League Division One side Featherstone Lions and Premier Division Lock Lane meet in the Ladbrokes Challenge Cup fourth round at Featherstone’s Big Fellas Stadium on Saturday (2.30pm).
The RFL ruled that Lions should switch the game to Featherstone Rovers from their own Mill Pond Stadium.
Lions team manager Keith Bell said: “Although we are disappointed at having to switch the game, we are now fully focused on the tie and we will have a full squad available for the first time this season.
“As underdogs against our Premier Division rivals, we are up for the challenge and ready to pull off an upset.”
Admission on Saturday will be £5 adults and £3 children and concessions.
The Lions-Lane ties means an amateur club is gauranteed a place in the fifth round.
Lions and Lock Lane both beat semi-professional League One clubs in the last round.
Lions defeated South Wales Scorpions 37-20 and Lane won 37-22 at Oxford.
The 12 winners of the fourth round ties will be joined in the next round by last year’s bottom four Super League clubs Hull KR, Salford, Widnes and Wakefield.